Abstract
This study was carried out to investigate the effects of adding baker yeast (BY), chlortetracycline (CTC) and both BY + CTC to a control diet containing 200 ng/g of aflatoxin B1 (C + AFB1) on performance, serum parameters and pathologyc alterations of broilers. A total 100 chicks (Ross PM 3) were divided into five groups in individual cages and each containing 20 animals. BY, a rich source of protein and vitamin B complex, was mixed into the diets at 2.0 %, CTC was mixed into the diet at 2.5 ng/g. Feed consumption, body weight and feed efficiency were recorded weekly. Serum parameters and pathologyc alterations were determined at the end of the study. Dead animals were recorded daily. Liver changes were clearly apparent in the C+AFB1and C+ AFB1+CTC most of the livers were enlarged, yellow and had pethecial hemorrhages. Canalicula cholestosis was absent in group C+AFB1 and C+ AFB1+CTC, but not others. When compared to the control (C) group, alkaline phosphatase (ALP), appear to be significantly increased in the C+AFB1 and C+CTC+ AFB1 groups. Serum glutamic oxalacetic transaminase (GOT)was increased in C+AFB1 birds. Serum alphaphetoprotein was not affected by the treatments. Feed consumption and body weight were significantly reduced in group AFB1. Birds receiving BY + AFB1, CTC + AFB1 and BY + CTC + AFB1 had a significantly higher body weight than group C+AFB1. Feed efficiency was better in group CTC + AFB1 than the others. The findings of this research suggest tha BY (2%) can partly counteract some of the toxic effects of AFB1.
Highlights
The occurrence of mycotoxins in foods and feeds is a problem of major concern in all over the world
If the lectins are bound to Mannan oligosaccharide (MOS), they can not bind to the epithelial cells and undesirable bacteria are eliminated from the gut lumen
Chlorotetracycline is a therapeutic antibiotic in poultry, effective in controlling signs of synovitis (Olson, 1976), in reducing numbers of Clostridium perfringens isolated from the ceca of birds infected with Eimeria tenella (Arakawa, 1975) and in reducing shed of Salmonella typhimurium in turkey poults (Nývas, 1976)
Summary
The occurrence of mycotoxins in foods and feeds is a problem of major concern in all over the world. Aflatoxins, a group of closely related and biologycally active mycotoxins, are produced by strains of Aspergillus flavus and Aspergillus parasiticus They commonly occur as natural contaminant of poultry feeds (Edds & Bortell, 1983). With the advent of using yeast cultures as growth promoters in poultry diets, several benefical effects have been recorded.Mannan oligosaccharide (MOS) is a product designed to influence microbial ecology. It is derived from yeast cell walls and it consists primarily on phosphorylated glucomannans. This study was conducted to determine the effect of dietary AFB1 (200 ng/g) when given baker yeast and CTC in growing broiler chicks
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