Reduction of motion artifacts for PET imaging by respiratory correlated dynamic scanning

Abstract

Organ motion caused by respiration is a major challenge in positron emission tomography (PET) imaging. This work proposes a technique to reduce smearing in PET imaging caused by respiratory motion. Dynamic scanning at 1 frame/s is used. A point source, used as a marker, is attached to the object's abdomen during the scan. The source position in the projection view moves with respiratory motion and can be used to represent the respiratory phase within the time interval in which each frame data are acquired. One hundred and twenty frames are obtained for each study. The range of the positions of the marker is divided into four groups, representing different respiratory phases. The frames in which the organ positions (phases) are the same summed to produce a static sub-sinogram. Each sub-sinogram then undergoes regular image reconstruction to yield a motion-free image. The technique is applied to one volunteer under both free and coached breathing conditions. A parameter called the volume reduction factor is adopted to evaluate the effectiveness of this motion-reduction technique. The preliminary results indicate that the proposed technique effectively reduces motion artifacts in the image. Coached breathing yields better results than free breathing condition. The advantages of this method are that (1) the scanning time remains the same; (2) free breathing is allowed during the acquisition of the image; and (3) no user intervention is required.