Abstract
Aqueous extracts of mouse uterine luminal epithelium have been shown to contain a factor which reduces mitosis in oestrogen-stimulated uterine epithelium, but not in vaginal epithelium or regenerating liver. The effect is transient and non-toxic, and occurs 3–4 hr after injection of the extract, with recovery by 6 hr, suggesting that there is a delaying action on cells in, or about to enter the G 2 phase of the cell cycle. This reduction in mitosis is not seen in response to aqueous extracts of mouse liver, or foreign proteins. Comparison of extracts prepared from uterine epithelia with high or low levels of proliferation, showed no difference in effectiveness.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
