Reduction of joint nociception induced by formalin in rats treated ith low level laser therapy 670 or 830 nm

Jhenifer Karvat,Assis R Escher,Jéssica A Malanotte,Gladson R F Bertolini,Daniele Pelissar,Camila M M Kakihata

doi:10.11606/issn.2176-7262.v48i6p533-538

Jhenifer Karvat, Assis R Escher + Show 4 more

Open Access

https://doi.org/10.11606/issn.2176-7262.v48i6p533-538

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Abstract

Study design: experimental study of cross-cutting nature. Objective: To evaluate the low level laser therapy (LLLT) effects, with a wavelength of 670 and 820nm, in nociception of Wistar rats submitted to hypernociception in his right knee. Methods: 18 Wistar rats, separated into 3 groups: G1 – untreated; G2 – treated with LBP 670 nm; G3 – treated with LBP 830 nm. For the hypernociception induction was injected into the tibiofemoral articular space 100 µL of 5% formalin. To evaluate nociception was used digital von Frey filament, both with pressure on the knee, as in the plantar region. The evaluations occurred: pre-injury (EV1), 15 (EV2), 30 (EV3) and 60 (EV4) minutes after hypernociception induction. For the treatment with LBP was used to 8 J/cm2, after EV2. Results: the withdrawal threshold, when the pressure was held at the knee, showed that 670 nm produced threshold elevation in EV3 and EV4, returning to values similar to those of EV1. For the plantar region, only 830 nm showed restoration of values in EV4, and was higher in EV3 when comparing with G1. Conclusion: Both wavelengths produced raising the paw withdrawal threshold in rats with knee hypernociception

Highlights

Study design: experimental study of cross-cutting nature
For the treatment with laser de baixa potência (LBP) was used to 8 J/cm[2], after EV2
Results: the withdrawal threshold, when the pressure was held at the knee, showed that 670 nm produced threshold elevation in EV3 and EV4, returning to values similar to those of EV1

Summary

ARTIGO ORIGINAL

Redução da nocicepção articular induzida pela formalina em ratos tratados com laser de baixa potência 670 ou 830 nm Reduction of joint nociception induced by formalin in rats treated ith low level laser therapy 670 or 830 nm Jhenifer Karvat[1], Camila M. Objetivo: avaliar os efeitos do laser de baixa potência (LBP), com comprimento de onda de 670nm e 820nm, na nocicepção de ratos Wistar submetidos à hipernocicepção articular no joelho direito. Para avaliar a nocicepção foi utilizado o filamento de von Frey digital, tanto com pressão sobre o joelho, quanto na região plantar; esta avaliação aconteceu: pré-lesão (AV1), após 15 (AV2), 30 (AV3) e 60 (AV4) minutos da indução da hipernocicepção. Resultados: o limiar de retirada, quando a pressão foi realizada no joelho, mostrou que 670 nm produziu elevação do limiar em AV3 e AV4, retornando para valores semelhantes aos de AV1. Apenas 830 nm mostrou restauração dos valores em AV4, e foi maior em AV3 ao comparar com o grupo controle. Conclusão: ambos os comprimentos de onda produziram elevação do limiar de retirada da pata, em ratos com hipernocicepção em joelho.

Grupos experimentais

Avaliação da nocicepção

Protocolo de tratamento com laser de baixa potência

Análise dos Dados