Reduction of Intubation Requirement in Coronavirus Disease 2019 Infection from the Fifth Dose of Coronavirus Disease 2019 Vaccine

Abstract

BACKGROUND: There is still no cure for coronavirus disease 2019 (COVID-19), which is a global emergency. The best choice for disaster management is vaccination. The principal COVID-19 preventive tactic of COVID-19 immunization is now widely accepted. Some scientists are advocating a fifth dosage vaccine in the event of the arrival of a new strain as well as the probable loss of public immunity following routine mass vaccination. AIM AND OBJECTIVE: The fifth dose of COVID-19 is typically reported to have successfully avoided mortality, although there is still concern about how to prevent severe COVID-19 cases that necessitate intubation. After receiving the fifth dosage of the COVID-19 vaccine, the authors of this study evaluated an extra protection rate that would reduce the need for intubation in COVID-19 infection. MATERIALS AND METHODS: The authors of this study employed a clinical model technique to assess an extra protection rate leading to a decrease in the need for intubation in COVID-19 infection following the fifth dose of COVID-19 vaccine immunization. RESULTS: According to the study, just four vaccine doses are required and are highly successful in preventing the need for intubation, thus there is no further benefit in this regard. However, the fifth dose may still be helpful in reducing the risk of contracting COVID-19. CONCLUSION: Clinical experiments have proven its efficacy in preventing omicron COVID-19 infection. However, there is no additional benefit in terms of lowering the need for intubation because just four immunization doses are necessary and extremely effective in doing so.