Abstract

As advances in cancer detection and treatment have increased the life expectancy of cancer patients, more attention to improving patient quality of life is needed. Among the various types of cancer pain, bone cancer pain is often debilitating, difficult to treat, and insufficiently relieved. Recently, a preclinical model of bone cancer pain has been developed [1]. This model has begun to provide insights into the mechanisms by which tumors cause pain and how cancer-pain-related sensory information is processed. Here we present new strategies for bone-cancer pain based on our data obtained from analyses of a mouse model. Murine model of bone-cancer pain

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