Abstract
In order to clarify the genesis of hemorrhagic lipemia, the following procedures were performed in rabbits; bleedings and injections of saline, plasma, corpuscle suspension, and macromolecular substance solution, respectively, simultaneous with bleedings. Then changes in plasma lipids and blood volume were studied once a day for three days. Separate injections of identical amounts of plasma and of corpuscle suspension, respectively, corresponding to twice the amount of blood withdrawn, inhibited the development of hemorrhagic lipemia and increased the blood volume. However, injections of isotonic saline corresponding to twice the amount of blood withdrawn failed to inhibit the occurrence of hemorrhagic lipemia and also failed to increase the blood volume. Injections of macromolecular substance solution in the same amount as blood withdrawn inhibited hemorrhagic lipemia. It is concluded, therefore, that the development of hemorrhagic lipemia in rabbits cannot be ascribed solely to bleeding, plasma removal or corpuscle removal, but is due to reduction in blood volume.
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