Abstract
The reductive coupling of aldimines and ketimines by a series of Sm(II)-based reagents (SmI2, SmI2–HMPA, SmBr2, Sm{N[Si(CH3)3]2}2, and SmI2/triethylamine/water) were examined. In general, aldimines and ketimines were efficiently reduced or coupled using reductants that are more powerful than SmI2, and the use of Sm{N[Si(CH3)3]2}2 led to higher diastereoselectivities in reductive coupling reactions. Surprisingly, only the combination of SmI2/triethylamine/water was capable of reducing and coupling para-substituted benzaldimines and coupling ketimines.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
