Abstract

Background HIV/AIDS and malnutrition are interrelated and exacerbate one another in a vicious cycle. As HIV infection progresses it causes catabolic state and increases susceptibility to other infections, leading to progressive aggravation of undernutrition. However, data are lacking in Ethiopia on determinants of undernutrition among people living with HIV on antiretroviral therapy. Therefore, this study aimed to assess determinants of undernutrition among adult HIV/AIDS patients in Northern Ethiopia. Method Facility-based unmatched case-control study was conducted among 324 randomly selected people living with HIV on antiretroviral therapy (ART). A structured and pretested interviewer questionnaire was used to collect data, while digital Seca weight and Seca measuring rod were used to measure weight and height, respectively. Logistic regression was used to identify independent factors of undernutrition, and p value <0.05 was declared for statistical significance. All statistical analyses were performed using SPSS 21™. Result This study revealed that people of younger age and those on ART (AOR = 0.29 (95% CI: 0.10, 0.84)) had low risk of being undernourished. However, average individual monthly income (AOR = 2.61 (95% CI: 1.48, 4.61)), not receiving nutritional counseling during visits (AOR = 2.5 (95% CI: 1.52–3.89)), and low diet diversity (AOR = 10.55 (95% CI: 4.17, 26.73)) had higher odds of undernutrition among people living with HIV/AIDS. Conclusion Age of patients, average monthly income, nutritional counseling during visits, and diet diversity were the independent factors of undernutrition. Counseling on well-timed and sufficient consumption of nutritious foods, economic strengthening, and livelihood activities is important. Future longitudinal study is necessary to elucidate the problem of undernutrition among people living with HIV/AIDS.

Highlights

  • human immunodeficiency virus (HIV)/AIDS and malnutrition are interrelated and exacerbate one another in a vicious cycle

  • Cases and controls were selected based on nutritional status of the patient measured using body mass index (BMI), of which patients whose BMI less than 18.5 kg/m2 were assigned as a potential case, whereas patients whose BMI greater than 18.5 kg/m2 were categorized as a potential control

  • This study indicated that people living with HIV on antiretroviral therapy (ART) who did not receive nutritional counseling were associated with undernutrition. is is similar to studies from Ethiopia [40], India [41], and Honduras [42], in which nutritional counseling improves dietary feeding practices

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Summary

Introduction

HIV/AIDS and malnutrition are interrelated and exacerbate one another in a vicious cycle. Data are lacking in Ethiopia on determinants of undernutrition among people living with HIV on antiretroviral therapy. Erefore, this study aimed to assess determinants of undernutrition among adult HIV/AIDS patients in Northern Ethiopia. Facility-based unmatched case-control study was conducted among 324 randomly selected people living with HIV on antiretroviral therapy (ART). Ethiopia had 380,000 estimated numbers of people living with HIV in Urban areas, with an adult prevalence of 3% with 98.6% of them receiving highly active antiretroviral treatment (HAART) in 2018. Prevalence of Journal of Nutrition and Metabolism undernutrition in Ethiopia ranges from 12%–34% among HIV/AIDS patients [7, 8]. The impact of HIV on nutrition has remained a concern as they interact in a vicious cycle [9]

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