Abstract
Mechanical ventilation contributes to bronchopulmonary dysplasia in preterm infants. We aimed to reduce the duration of ventilation by weaning ventilator settings within 1 h of “weanable” blood gases and extubating within 1 h of a “weanable” blood gas on “extubatable” ventilator settings. Infants born at < 32 weeks/< 1500 g were included. “Weanable” blood gases and “extubatable” ventilator settings were defined. Interventions included: a multidisciplinary BPD prevention team, extubation criteria, NICU education, a process for rapid notification of medical staff about all blood gas results, and monthly data dissemination. Extubations within 1 h of criteria increased from 64% to 88% after the dissemination of guidelines and education. The time to extubation decreased from 325 to 49 min, and the duration of intubation decreased from 8 to 3 days. However, the time for ventilator weaning did not change. Re-intubation rates did not change. Standardization of extubation led to decreased duration of mechanical ventilation.
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