Reduced Intensity Conditioned (RIC), HLA-haploidentical BMT in AML

Abstract

S190 conclusion, this study highlights the importance of the microenvironment in the anti-leukemia effect of G-CSF in AML patients, and suggests that G-CSF exerts its effect at least partially on LSCs. The observed correlation between the degree of reduction of clonogenic capacity of primary AML cells and clinical response to induction chemotherapy is in keeping with previously reported benefit of concurrent G-CSF and chemoimmunotherapy treatment in some AML forms. Age, median 54 57 55 43 de Novo 58 2 45 11 Secondary 40 12 25 3 Status at BMT 221