Abstract
BackgroundThe ageing process may lead to reductions in physical fitness, a known risk factor in the development of metabolic syndrome. The purpose of the current study was to evaluate cross-sectional and combined associations of metabolic syndrome with body composition and physical fitness in a community based geriatric population.MethodsA total of 628 community-dwelling elders attending a geriatric health examination were enrolled in the study. The diagnosis of metabolic syndrome was based on the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criterion with Asian cutoff of waist girth was adopted in this study. Body composition was obtained using bioimpedance analysis, and physical fitness was evaluated through the measurement of muscle strength (handgrip force), lower extremity muscle endurance (sit-to-stand test), flexibility (sit-and-reach test), and cardiorespiratory endurance (2-minute step test). Multivariable logistic regression and correlation analysis were performed to determine the association of metabolic syndrome with body composition and functionality variables.ResultsMetabolic syndrome was associated with increased skeletal muscle index (SMI) (odds ratio (OR), 1.61, 95% confidence interval (CI), 1.25–2.07) and decreased flexibility (OR, 0.97, 95% CI, 0.95–0.99) compared with those without metabolic syndrome. When body mass index was accounted for in the analysis, the association of SMI with metabolic syndrome was reduced. Waist circumference was positively correlated with SMI but negatively correlated with flexibility, whereas high density lipoprotein was positively correlated with flexibility but negatively correlated with SMI.ConclusionReduced flexibility was positively associated with metabolic syndrome independent of age, gender, body composition, and functionality measurements in a community based geriatric population. Significant associations between metabolic syndrome with muscle strength and cardiorespiratory fitness in the elderly were not observed. Furthermore, flexibility should be included in the complete evaluation for metabolic syndrome.
Highlights
Metabolic syndrome is a combination of several metabolic disorders encompassing visceral obesity, insulin resistance, dyslipidemia, and hypertension [1]
Metabolic syndrome was associated with increased skeletal muscle index (SMI) (odds ratio (OR), 1.61, 95% confidence interval (CI), 1.25–2.07) and decreased flexibility (OR, 0.97, 95% CI, 0.95–0.99) compared with those without metabolic syndrome
Reduced Flexibility in Metabolic Syndrome correlated with flexibility, whereas high density lipoprotein was positively correlated with flexibility but negatively correlated with SMI
Summary
Metabolic syndrome is a combination of several metabolic disorders encompassing visceral obesity, insulin resistance, dyslipidemia, and hypertension [1]. Regarding similar studies using a large sample, Jurca et al recruited 8570 participants with ages ranging from 20 to 75 years, and found a negative association between leg strength and prevalence of metabolic syndrome, even after adjustment for cardiorespiratory fitness [6]. To the best of our knowledge, few studies have investigated the relationship between metabolic syndrome and health-related physical fitness in urban senior citizens, and the influence of body composition [11, 12]. The aim of the current study was to compare crosssectional relative and combined associations of metabolic syndrome with body compositions, flexibility, muscle strength and cardiorespiratory fitness in a community based geriatric population. The purpose of the current study was to evaluate crosssectional and combined associations of metabolic syndrome with body composition and physical fitness in a community based geriatric population
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
