Abstract

The formation of the melanosome – the organelle responsible for synthesizing the melanin pigment found in hair, skin, and eyes – has long been studied as a model for the specialized development of organelles. In part this is due to the relative ease in identifying genes that impact pigmentation based on subtle to severe forms of albinism. The melanosome belongs to a family of lysosome-related organelles (LROs) that share some characteristics including an acidic lumen, part of their protein content, and biogenesis mechanisms. This article is protected by copyright. All rights reserved.

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