Abstract

Background: Research shows that transcranial direct current stimulation is effective in reducing depression and anxiety. Objectives: This research is aimed at reducing depression and anxiety in methadone users with transcranial direct current stimulation. Methods: This study is a randomized clinical trial with a pretest-posttest. The sample of this study was 60 methadone users who had severe depression and anxiety. Participants were allocated to two experimental (n = 30) and control groups (n = 30). The two regions, F3 (cathode) and F4 (anode) were stimulated with a current of 2 mA for 20 minutes in 10 sessions. Participants were assessed before and after stimulation with Beck’s depression inventory and Berger’s anxiety test. Results: Data analysis showed that tDCS reduced the symptoms of depression and anxiety in methadone users (P < 0.01). Conclusions: It seems that the method of tDCS can reduce the severity of symptoms of depression and anxiety. Therefore, it can be claimed that this intervention can be considered by experts as a complementary intervention along with other psychological and pharmacological treatments.

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