Abstract
• Na + ,K + -ATPase activity alternates with freeze-thaw cycles. • Na + ,K + -ATPase changes membrane microlocation between lipid rafts and bulk membrane. • Na + ,K + -ATPase redistribution is accompanied by reshuffling of specific gangliosides. • Ganglioside GM1 distribution reflects Na + ,K + -ATPase protein distribution. • GD1a, GD1b and GT1b distribution mirrors the changes in Na + ,K + -ATPase activity.
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