Abstract
HPLC with EC detector was used to study the red light effect on the rhythmicity of catecholamines (NE, DOPAC and dopamine) and indoleamines (NAS, 5-HT, 5-HIAA) in the pineal glands and retinas of the Sprague-Dawley rat. We found the prominent nocturnal elevations of NAS in rat pineal glands and the suppression of the NAS but not the elevation of 5-HT and 5-HIAA after red light exposure at night. Our data show two findings: metabolic pathway of the indoleamines (5-HT, 5-HIAA and NAS) after red light exposure at night may be different from those by white light. Second, the increased HIOMT activity that effects on 5-HT and 5-HIAA may also be involved in the indoleamine formation after red light exposure at night.
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