Red fingers syndrome in a patient with pseudolymphoma

Abstract

To the Editor: A 31-year-old woman presented with a 10-year history of erythematous plaques on the face consistent with cutaneous pseudolymphoma. She incidentally was noted to also have dusky discoloration of her distal fingers and hypothenar eminences bilaterally (Fig 1), but not toes, and without associated pain, numbness, or accentuation in the cold. Onycholysis was noted on several fingernails, but clubbing or periungual telangiectasias were not present. The patient related that the redness was not present at birth and appeared during her adult years before her pseudolymphoma lesions. She also noted that the redness appeared on the fingers and palms simultaneously and did not wax and wane. She was not using any prescribed or over-the-counter medications at the time of onset or at presentation. She further denied use of alcohol or illicit drugs and was otherwise without medical problems. Screening serologies for HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), Lyme disease and mononucleosis produced unremarkable findings. A biopsy was offered, but the patient declined as the redness was asymptomatic. She had complete clearance of pseudolymphoma lesions with interferon alfa-2b therapy, 1 Singletary H.L. Selim M.A. Olsen E.A. Subcutaneous interferon alfa for the treatment of cutaneous pseudolymphoma. Arch Dermatol. 2012; 148: 572-574 Crossref PubMed Scopus (7) Google Scholar but no change in the distal finger discoloration was observed.