Abstract

A procedure for recyclable asymmetric cyclization leading to optically active Wieland-Miescher ketone analogue has been developed employing D-phenylalanine and D-CSA in [hmim]PF 6 and dimethylimidazolidinone in 81% chemical yield and 74% enantiomeric excess in average after five uses. A Hajos-Wiechert ketone analogue was also synthesized in a similar manner.

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