Abstract
Vacuolar myelopathy is the major cause of spinal cord disease in HIV-1 infection. However, the pathogenesis remains unclear. Diagnosis is mainly based on characteristic clinical symptoms in combination with characteristic MRI changes. Usually, it is a slowly progressive chronic disease affecting HIV-infected individuals with low CD4 T-cell counts. Here, we report an uncommon case of vacuolar myelopathy in an HIV-infected woman with recurrent clinical symptoms and MRI changes of vacuolar myelopathy and with a preserved CD4 T-cell count when symptoms occurred for the first time. This is the first case, to show that vacuolar myelopathy can have relapsing-remitting clinical symptoms and MRI changes.
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