Abstract
Transfusion-related acute lung injury (TRALI) is a rare clinical syndrome. The risk of a patient having more than one attack is very low. Clinical findings are dyspnea, hypoxemia, hypotension, bilateral pulmonary edema and fever. Granulocyte antibodies, human leukocyte antigen-1 (HLA)-1, HLA-2 antibodies and biologically active lipids like lysophosphatidylcholine in donor plasma are known to play a role in the pathophysiology of the disease. Triggering factors include sepsis, cytokine administration, recent history of surgery and massive blood transfusion. In this article, we report a case of 1.5-year-old girl operated due to congenital heart disease with frequent blood product transfusions and having TRALI attacks for four times, who recovered after cessation of blood product transfusions and supportive therapy.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
