Recurrent staphylococcal infection of the face associated with the development of anti-Dsg3 antibody response

Abstract

The etiopathogenesis of the Tunisian pemphigus is still ambiguous. Indeed, the complete mechanism, which goes from the causal agent until the final targets, is unknown. Nevertheless, two types of factors were associated in the etiopathogenesis of the pemphigus: genetic and/or environmental factors. We focused our intention in bacterial infectious etiology due to staphylococcus. We report a 42-year-old man presenting staphylococcal infection: anti-desmogleines antibody (1 and 3) at the first infection was negative. Surprisingly, he became positive for anti-Dsg3 antibodies after having relapsed.