Recurrent sinonasal teratocarcinosarcoma treated with IMRT: a case report

Abstract

<p class="abstract">Sinonasal teratocarcinosarcoma is a rare malignant tumour displaying aggressive growth .It is known to have poor prognosis with locoregional recurrence. So far, the most widely accepted therapeutic plan for its management has been surgery followed by adjuvant radiation. This study reports a case of 35 year old male diagnosed with sinonasal undifferentiated carcinoma who presented with neck node recurrence after 15 months of definitive radiotherapy. A 35 year old patient presented with nasal obstruction and epistaxis. CECT PNS revealed mass in ethmoid sinus with adjacent bony destruction and infiltration into maxillary sinus and nasal cavity. Biopsy revealed poorly differentiated carcinoma. Patient underwent neoadjuvant chemotherapy followed by definitive radiotherapy by IMRT. On follow up at 15 months, the patient presented with nodal recurrence. Biopsy from neck node revealed metastatic sinonasal teratocarcinosarcoma. The patient underwent neck dissection followed by adjuvant chemoradiation. The patient is currently on follow up and is disease free till date. Surgery alongwith adjuvant chemoradiation is a reasonable therapeutic approach of management for sinonasal teratocarcinosarcoma.</p><p class="abstract"> </p>