Abstract

We describe the first isolation in France of a New-Delhi metallo-beta-lactamase-1 (NDM-1) producing Pseudomonas aeruginosa. In March 2012, a patient with history of prior hospitalisation in Serbia was diagnosed in France with acute pyelonephritis due to NDM-1 producing P. aeruginosa. Clinical and microbiological cure was obtained under appropriate antibiotic treatment. Two months later, she presented with a recurrence due to the same bacteria, with a favourable evolution. During both hospitalisations, contact isolation precautions were implemented and no cross-transmission was observed.

Highlights

  • We describe the first isolation in France of a NewDelhi metallo-beta-lactamase-1 (NDM-1) producing Pseudomonas aeruginosa

  • Among 77 patients infected or colonised by NDM-1 producing Enterobacteriaceae reported in Europe from 2008 to 2010, five had been hospitalised previously in the Balkan region [6]

  • We report here the first case of infection due to NDM-1-producing P. aeruginosa in France

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Summary

Rapid communications

Recurrent pyelonephritis due to NDM-1 metallo-betalactamase producing Pseudomonas aeruginosa in a patient returning from Serbia, France, 2012. We describe the first isolation in France of a NewDelhi metallo-beta-lactamase-1 (NDM-1) producing Pseudomonas aeruginosa. In March 2012, a patient with history of prior hospitalisation in Serbia was diagnosed in France with acute pyelonephritis due to NDM-1 producing P. aeruginosa. Clinical and microbiological cure was obtained under appropriate antibiotic treatment Two months later, she presented with a recurrence due to the same bacteria, with a favourable evolution. In March 2012, a patient with a history of prior hospitalisation in Serbia was diagnosed in France with acute pyelonephritis due to New Delhi metallo-beta-lactamase-1 (NDM-1) producing Pseudomonas aeruginosa

Case report
Antimicrobial sensitivity testing and molecular diagnostics
Monitoring of plasmatic and urinary concentrations of antibiotics
Discussion and conclusion
Full Text
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