Abstract
Summary: We report a 29‐year‐old man with renal failure due to focal and segmental glomerulosclerosis (FSGS) who received a well‐matched cadaveric renal allograft and had the early appearance of the nephrotic syndrome and renal insufficiency. His condition responded dramatically to plasmapheresis. the pathogenesis of FSGS recurring in a renal allograft may involve a recently identified circulating factor. the possible efficacy of plasmapheresis in the treatment of recurrent FSGS may be attributable to the removal of this factor.
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