Recurrent multifocal conjunctival melanoma originated from preexisting pigmented nevus

Marcos Leandro Pereira,Dulcídio De Barros Moreira Júnior

doi:10.5935/0034-7280.20140039

Abstract

Recurrent multifocal conjunctival melanoma originated from preexisting nevus is extremely rare: it occurs in one out of five million individuals. The investigation of this disease is extremely important due to its potential lethality. Thus, this study aims to describe a case of recurrent multifocal conjunctival melanoma originated from preexisting pigmented nevus, which occurred in the city of Patos de Minas, state of Minas Gerais. This is a case study and literature review. Histopathological diagnosis and early staging of the conjunctival [...]

Highlights

Conjunctival neoplasms include a broad spectrum of benign and malignant lesions, some of which can impair visual acuity or result in an aggressive malignancy that can rarely lead to death[1,2].A broad variety of neoplasms and pseudoneoplasms originate from the melanocytic system
This paper aims to describe a case of recurrent multifocal conjunctival melanoma arising from a pre-existing pigmented nevus in a patient from Patos de Minas/MG, Brazil
Each type of melanocyte can cause numerous types of pigmented lesions. Among those derived from dendritic melanocytes are benign pigmented melanosis, secondary acquired melanosis of the conjunctiva, and primary acquired melanosis

Summary

Introduction

Conjunctival neoplasms include a broad spectrum of benign and malignant lesions, some of which can impair visual acuity or result in an aggressive malignancy that can rarely lead to death[1,2].A broad variety of neoplasms and pseudoneoplasms originate from the melanocytic system. Conjunctival melanoma, a rare and aggressive malignant tumour, can develop from a primary acquired melanosis, a melanocytic nevus, normal tissue, or the palpebral conjunctiva[3,4]. It can be congenital or appear in the first decades of life. Conjunctival nevi can be pigmented or not They are melanocytes that migrate to the sclera, the episclera or the proper substance but do not reach the epithelium. Such lesions are often multifocal and tend to recur when excised[6]

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