Recurrent Malignant Fibrous Histiocytoma of the Right Atrium with Extracardiac Extension

Abstract

4Department of Pathology, Soonchunhyang University Hospital Bucheon, Bucheon, Gyunggi, 420-767, Korea. primary cardiac malignant fibrous histiocytoma (MFH) of the right atrium was diagnosed in a 34year-old woman admitted to our hospital with dyspnea. Pathohistological examination confirmed MFH. The tumor recurred rapidly, and a second operation was not performed. A CT chest scan revealed a large mass in the right atrium with extracardiac extension. The patient was treated with chemotherapy using a combined drug regimen. Despite hemodynamic impairment and extracardiac extension, adjuvant chemotherapy promoted partial remission. We report a case of recurrent primary cardiac MFH with extracardiac extension and successful chemotherapeutic management. Primary cardiac tumors are uncommon and most are benign. Malignant tumors account for only 25% of all primary cardiac tumors [1, 2]. Most malignant cardiac tumors are angiosarcomas. Malignant fibrous histiocytomas are rare primary cardiac tumors [3–6]. We report on a case of recurrent primary cardiac MFH with extracardiac extension and successful chemotherapeutic management.