Abstract
Apocrine carcinomas arise from normal or modified sweat glands. The slow-growing nature and rarity of sweat gland carcinomas complicate their diagnosis at the early stage. The incidence of PASGC is quite low at 0.0049–0.0173 cases/100,000 persons/year. A 21-year-old male patient was presented in February 2016 with small solitary mass in the right axilla with mild tenderness and pain. Underwent wide local excision and axillary dissection at our institution followed by adjuvant radio and chemotherapy. Later on, after 18 months developed local recurrence and was planned for re-surgery and a second phase of palliative radiotherapy. After a year, presented to the hospital with pin sized irregular swelling in the axilla. Sweat gland carcinomas which are rarely diagnosed create a pathological dilemma due to their unpredicted biological behavior. However, wide local excision with or without nodal dissection is the primary treatment till date. In this particular case even though patient had underwent axillary node dissection, patient had recurrence twice with no distant metastasis which is a key point to be noted. Thorough study of the available apocrine carcinoma case reports or case series, the better knowledge regarding the apocrine carcinoma can be obtained.
Highlights
Apocrine carcinoma usually appears as a single, small nodule or a multinodular mass which is characterized by symptomatic progression
Among all the tumor specimens resected surgically, sweat gland carcinoma is found to be very rare with an incidence of
He presented to the hospital with pin sized irregular swelling in the axilla. He had been advised with further investigations, but patient was not on follow-up, which was a minor drawback in this case report. Based upon their histological behavior, sweat gland carcinomas can be classified as apocrine and eccrine
Summary
Apocrine carcinoma usually appears as a single, small nodule or a multinodular mass which is characterized by symptomatic progression. Post HPE report indicates nodular invasive tumor, PNI noted and mentioned as RECURRENT MALIGNANT SWEAT GLAND CARCINOMA-APOCRINE CARCINOMA (Fig. 3). He received a second string of palliative radiotherapy for a dose of 30 Grays in 10 fractions. The benefit of continuing treatment plan was stressed and need for follow-up treatment was discussed After a year, he presented to the hospital with pin sized irregular swelling in the axilla. He presented to the hospital with pin sized irregular swelling in the axilla He had been advised with further investigations, but patient was not on follow-up, which was a minor drawback in this case report
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