Recurrent Larynx and Hypopharyngeal Liposarcoma with Systemic Progression

Abstract

Introduction: Liposarcomas are infrequent tumors. Only 5.6% of these tumors occur in the head and neck. Primary liposarcomas of the larynx comprise ∼10% to 15% of head and neck liposarcomas. Multiple surgeries and recurrences history are common. Case summary: We present the case of a 33-year-old male whose illness started at 16 years of age, and who underwent multiple surgeries due to multiple recurrence (six) by a liposarcoma in the neck, all treated with organ preservation. In 2014 patient arrived with a big recurrence a total pharyngolaryngectomy with a jejunal are flap was performed. after 18 month of the follow up the patient comes to the visits and refered developed headache, ataxia and shortness of breath, that is why a MRI of the brain and CT of the torax shown intraxial lesions in the brain and multiple bilateral pulmonary nodules compatible with metastatic disease, We propose palliative treatment with radiotherapy but the patient refuse treatment so he was sent to palliative care. Discussion: The mainstay of treatment is surgical resection. Multiple recurrence is the rule but metastasis to the brain was not reported before. The role of radiotherapy is not well know. Chemotherapy until now showed no sustancial benefit.