Abstract
Hydatidiform mole is the most common form of gestational trophoblastic disease. Recurrent molar pregnancies are extremely rare. Herein, we reported the case of a patient with five consecutive molars; four of them were complete mole, and one was partial mole complicated by HELLP syndrome and DIC.
Highlights
Hydatidiform mole is characterized by atypical hyperplastic trophoblasts and hydropic villi
PET is the new onset of hypertension (BP ≥ 140 mmHg systolic, ≥90 mmHg diastolic measured on two separate occasions) and proteinuria (≥0.3 g/day) after 20-week gestation in a previously normotensive patient
HELLP is considered as the severe form of PET when BP is ≥160 mmHg systolic and ≥110
Summary
Hydatidiform mole is characterized by atypical hyperplastic trophoblasts and hydropic villi. It forms a heterogeneous group of disorders, with an incidence ranging from 1/500 to 1/1500 pregnancies. Recurrent molar pregnancies are rare, its incidence is 1% - 2% of all molar; it’s clear that women who have a previous mole have a higher risk of recurrence than the general population [4]. PET is the new onset of hypertension (BP ≥ 140 mmHg systolic, ≥90 mmHg diastolic measured on two separate occasions) and proteinuria (≥0.3 g/day) after 20-week gestation in a previously normotensive patient. Case reports have reported very early PET (before 20-week gestation) in association with molar pregnancy, triploidy, Cushing syndrome and antiphospholipid syndrome. HELLP is considered as the severe form of PET when BP is ≥160 mmHg systolic and ≥110. MmHg diastolic measured, and or headache, blurred vision, epigastric pain, and hematological manifestation
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