Recurrent Human Granulocytic Ehrlichiosis and Lyme Disease

Abstract

Letters15 June 1999Recurrent Human Granulocytic Ehrlichiosis and Lyme DiseaseHarold W. Horowitz, MD, Maria E. Aguero-Rosenfeld, MD, and Gary P. Wormser, MDHarold W. Horowitz, MDWestchester Medical Center; Valhalla, NY 10595 (Horowitz)Westchester Medical Center; Valhalla, NY 10595 (Aguero-Rosenfeld)Westchester Medical Center; Valhalla, NY 10595 (Wormser)Search for more papers by this author, Maria E. Aguero-Rosenfeld, MDWestchester Medical Center; Valhalla, NY 10595 (Horowitz)Westchester Medical Center; Valhalla, NY 10595 (Aguero-Rosenfeld)Westchester Medical Center; Valhalla, NY 10595 (Wormser)Search for more papers by this author, and Gary P. Wormser, MDWestchester Medical Center; Valhalla, NY 10595 (Horowitz)Westchester Medical Center; Valhalla, NY 10595 (Aguero-Rosenfeld)Westchester Medical Center; Valhalla, NY 10595 (Wormser)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-130-12-199906150-00101 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail IN RESPONSE:Dr. Johnson comments that our patient with recurrent human granulocytic ehrlichiosis and recurrent Lyme disease did not develop antibodies to B. burgdorferi after her initial infection in 1994. Lack of seroreactivity to Lyme borrelial antigens has been reported to occur in about 10% of treated patients with culture-proven erythema migrans when serial antibody testing is done (1), for reasons not yet established. Dr. Johnson also makes the point that after the second episode of erythema migrans in July 1997, the Western blot became negative by 3 months whereas the ELISA result remained positive. He notes that the ELISA ...