Abstract
Congenital syphilis is still a public health issue worldwide. Beyond the neonatal period, clinical findings may be subtle and nonspecific. We report an unusual case of congenital syphilis with recurrent fever, knee pain and severe anemia in a 28 month-old boy, despite standard penicillin treatment early in life. Congenital syphilis should be considered throughout early childhood, especially if past or familiar medical story of syphilis.
Highlights
Congenital syphilis is still a public health issue worldwide
We report an unusual case of congenital syphilis with recurrent fever, knee pain and severe anemia in a 28 month-old boy, despite standard penicillin treatment early in life
Case Report A 28-month-old boy was referred to our pediatric rheumatology department for suspected Still’s disease
Summary
Congenital syphilis is still a public health issue worldwide. Clinical findings may be subtle and nonspecific. We report an unusual case of congenital syphilis with recurrent fever, knee pain and severe anemia in a 28 month-old boy, despite standard penicillin treatment early in life. Congenital syphilis should be considered throughout early childhood, especially if past or familiar medical story of syphilis. Posterior serological evaluations revealed a negative VDRL and declining of TPHA until 1:2560 in the second year of life. At 20 month-old he was referred to the orthopedics hospital department because of a bilateral genu varum.
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