Abstract

BackgroundChronic inflamed tissue in nasal cavity is a rare complication of transsphenoidal approach (TSA). Inflamed tissue is rich in blood vessels, which can lead to frequent nosebleeds. In addition, chronic inflammation can cause pseudoaneurysm, whose rupture results in massive epistaxis. There have been few reported cases of pseudoaneurysm of ICA occurring more than 10 years after TSA surgery.Case presentationWe report a case of a patient who had recurrent epistaxis for over a decade after TSA surgery, and analyzed the causes of the nosebleeds. The aspect of occurrence of the nosebleeds and the result of biopsy and imaging tests suggest that the nosebleeds were due to chronic inflamed tissue and an associated pseudoaneurysm. The rupture of pseudoaneurysm recurred after treatment with stent placement, and brain abscess was developed. After removing the inflamed tissue by endoscopic resection, the patient no longer had recurrence of ruptured pseudoaneurysm or nosebleeds.ConclusionsIn patients with recurrent nosebleeds, the possibility of intranasal inflammation and subsequent pseudoaneurysm should be considered. Therefore, people who consistently have epistaxis after TSA, even if the bleeding is not in large amount, should be actively screened and treated for nasal chronic inflammation.

Highlights

  • Chronic inflamed tissue in nasal cavity is a rare complication of transsphenoidal approach (TSA)

  • Massive epistaxis from a ruptured pseudoaneurysm of the internal carotid artery (ICA) is a rare but serious complication of the transsphenoidal approach (TSA). This complication usually occurs within a few weeks after surgery, and there have been no reported cases of delayed rupture of pseudoaneurysm occurring more than 10 years after surgery

  • Emergent endoscopy revealed a bleeding focus on the anterior wall of the right sphenoid, and computed tomography (CT) angiography demonstrated a pseudoaneurysm in the right ICA that recovered from rupture in the area of the previous TSA

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Summary

Introduction

Chronic inflamed tissue in nasal cavity is a rare complication of transsphenoidal approach (TSA). We describe a case of recurrent epistaxis that occurred more than 10 years after TSA surgery, and discuss the effects of chronic inflammation in the formation of a pseudoaneurysm and the development of brain abscesses. The patient had intermittently suffered nosebleeds and blood-tinged sputum (which is thought to be posterior nasal drip) after undergoing TSA surgery in 2006, and the symptoms worsened in the latest 1 month; he decided to visit the hospital.

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