Recurrent cholestasis of pregnancy. Treatment with cholestyramine of one case with an unusually early onset.

Abstract

Abstract. This is a report of a 28‐year‐old woman with cholestasis occurring in the first month of gestation in four consecutive pregnancies. During the interval between the third and fourth pregnancy as well as during and after the fourth one the patient was regularly examined with regard to her liver function. Intensive itching and markedly elevated serum bile acids were the predominant symptom and laboratory finding during the fourth pregnancy. Both decreased during cholestyramine treatment. The bromsulphalein retention was quite normal six months after the third pregnancy but is still elevated two and a half years after the last one.