Abstract
A 24-year old female presented to the accident and emergency department with collapse. Eight days prior to presentation she had undergone cystoscopy for chronic urinary symptoms. She was commenced on oral trimethoprim after the procedure. The following day she became unwell with retro-orbital headache, photophobia, and nausea. She omitted her trimethoprim for the next six days and symptoms improved. On day seven she restarted her trimethoprim and within 10 minutes experienced a severe recurrence of her symptoms prompting admission to hospital.
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