Recurrent aggressive multicystic ameloblastoma with hemangiomatous proliferation and giant cells: A perplexed diagnosis

Abstract

Hemangiomatous ameloblastoma, a very rare variant of ameloblastoma, was originally described as ameloblastoma in which part of the tumor contained spaces filled with blood or large endothelial-lined capillaries. Ameloblastoma, the most commonly affecting a slow-growing, persistent, and locally aggressive neoplasm of epithelial origin, account for a major chunk of all odontogenic tumors. A 43-year-old female reported to our outpatient department with a rare association of multicystic ameloblastoma with unusual hemangiomatous proliferation (both in lining and the stroma) along with giant cells in the lesional tissue. There are <8 cases documented in the literature with the same histologic features and most are in the middle age with the mandibular location.