Recuento de linfocitos CD4 e infecciones oportunistas en pacientes con VIH en un hospital de Chiclayo, Perú, 2020

Abstract

Objective. To determine the relationship between CD4 lymphocytes with opportunistic infections in patients with HIV infection in a hospital in Chiclayo, Peru, 2020. Material and methods: The study was observational, retrospective and analytical cross-sectional, the study population was 135 medical records. of patients with a confirmed diagnosis of HIV-AIDS who were treated in the infectious disease service. Results: The male sex predominated (81.5%), 97.8% were between 18 and 59 years old and were mostly single (69.6%). The most frequent infections were gastroenteritis (29.6%), tuberculosis (9.6%) and toxoplasmosis (8.1%), the majority presented a CD4+ lymphocyte count less than 200 cells/uL, in addition the most frequent clinical stages were B3 and B2 (42.2%). An association was found between the frequency of opportunistic infections and the CD4+ count (p=0.001), these were more frequent in patients with a CD4+ lower than 200 cells/uL (71.4%). Conclusions: The study population had a high frequency of opportunistic infections, which were associated with a CD4+ lymphocyte count of less than 200 cells/uL.