Abstract
The absorption profiles and bioavailability of morphine in human volunteers ( n = 13) were described after oral administration of MS Contin tablets and rectal administration of a newly developed controlled release suppository. By manipulating the viscosity of fatty suppository base an entirely identical cumulative morphine input could be obtained compared with oral dosing.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have