Abstract

BackgroundCoronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide. Despite abundant data on that many COVID-19 patients also displayed kidney disease, there is limited information available about the recovery of kidney disease after discharge.MethodsRetrospective and prospective cohort study to patients with new-onset kidney disease during the COVID-19 hospitalization, admitted between January 28 to February 26, 2020. The median follow-up was 4 months after discharge. The follow-up patients were divided into the recovery group and non-recovery group. Descriptive statistics and between-groups comparison were used.ResultsIn total, 143 discharged patients with new-onset kidney disease during the COVID-19 hospitalization were included. Patients had a median age was 64 (IQR, 51–70) years, and 59.4% of patients were men. During 4-months median follow-up, 91% (130 of 143) patients recovered from kidney disease, and 9% (13 of 143) patients haven’t recovered. The median age of patients in the non-recovery group was 72 years, which was significantly higher than the median age of 62 years in the recovery group. Discharge serum creatinine was significantly higher in the non-recovery group than in the recovery group.ConclusionsMost of the new-onset kidney diseases during hospitalization of COVID-19 patients recovered 4 months after discharge. We recommend that COVID-19 patients with new-onset kidney disease be followed after discharge to assess kidney recovery, especially elderly patients or patients with high discharge creatinine.

Highlights

  • Coronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide

  • Zhang et al BMC Infectious Diseases (2021) 21:397 to date have been limited to observations during hospitalization, so the recovery of kidney disease remains unknown in COVID-19 patients who survive after hospitalization

  • During a median follow-up of 4 months, we found that 91% of COVID-19 patients recovered from new-onset kidney disease

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Summary

Introduction

Coronavirus disease 2019 (COVID-19) has emerged as a major global health threat with a great number of deaths worldwide. Despite abundant data on that many COVID-19 patients displayed kidney disease, there is limited information available about the recovery of kidney disease after discharge. The ongoing coronavirus disease 2019 (COVID-19) is a worldwide pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [1, 2]. COVID-19 is a respiratory infectious disease that primarily causes pneumonia and severe hypoxemia, but. Zhang et al BMC Infectious Diseases (2021) 21:397 to date have been limited to observations during hospitalization, so the recovery of kidney disease remains unknown in COVID-19 patients who survive after hospitalization. We aimed to describe the incidence and short-term recovery of new-onset kidney disease during hospitalization in COVID-19 patients who discharged alive

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