Abstract
Using sodium aspartate Ringer's we recorded gross potentials from the receptors of the frog's isolated retina. With appropriate selection of stimulating conditions, dark adaptation of the 580 cones was studied. After intense lights that bleach substantial cone pigment and raise cone threshold over 2 log units, the cones recover nearly all their sensitivity, within 0.16 log unit. This is in marked contrast to the 502 rods (see following paper) and is consistent with Goldstein's ERP evidence that indicates 580 cone pigment regeneration in the isolated retina.
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