Recovery, not progressive deterioration, should be the expectation in schizophrenia.

Abstract

Since the time of Kraepelin, schizophrenia has been considered to be a progressive deteriorating illness (1). This perspective has been bolstered by a generation of studies demonstrating deficits in brain volumes on magnetic resonance imaging (MRI) scans and in performance on a broad range of cognitive tasks in individuals with schizophrenia (2).