Abstract
Non-traumatic clostridial infections present either as septicæmia or as a metastatic localised lesion. Almost all such infections occur in elderly debilitated patients with ulcerating lesions in the gastrointestinal, biliary, or genitourinary tracts. In addition, most cases have developed in diabetics or in patients receiving cancer chemotherapeutic agents. All eight reported cases of non-traumatic clostridial myonecrosis have died of overwhelming clostridial infection, usually within 24 hours. The case described here was recognised early and treated promptly by debridement of necrotic muscle and by hyperbaric oxygen. This 74-year-old man recovered completely from the gas gangrene, though he died 3 weeks later with widespread gram-negative sepsis.
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