Abstract
This study examined the bioavailability of iron contained in microencapsulated ferric saccharate in a rat model of iron deficiency anaemia. Three groups of male Sprague-Dawley rats with induced iron deficiency anaemia were subsequently treated with a control Fe-deficient diet (2-6mg Fe/Kg of diet) with or without the addition of 10mg Fe/Kg of diet (in form of ferrous sulphate or microencapsulated ferric saccharate) for 2weeks. The bioavailability of microencapsulated ferric saccharate was examined by measuring body weight gain, feed efficiency and reticulocyte parameters, and compared with the bioavailability of ferrous sulphate. Final body weight, feed efficiency, mean corpuscular volume of reticulocytes and average haemoglobin content in reticulocytes were significantly higher in anaemic rats supplemented with either microencapsulated ferric saccharate or ferrous sulphate, compared to anaemic controls. No significant differences were found between the two iron-supplemented groups. The total number of reticulocytes showed a similar trend. The results demonstrated that ingestion of microencapsulated ferric saccharate is as effective as ferrous sulphate in recovery from iron deficiency anaemia.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
