Abstract
Optical imaging has attracted recent attention as a non-invasive medical imaging method in biomedical and clinical applications. In optical imaging, a light beam is transmitted through an under-test tissue by using an optical source. The beams which are gone through the tissue and/or reflected from the tissue surfaces are received by an array sensor. Based on the light intensity of these received beams on the sensor, sub-tissue maps are generated to scan large tissue areas so that any further biopsy is not required. Although the large tissue areas in pathological images can be scanned by using various methods, nonlinear deformations occur. To overcome this problem, the reconstruction process is frequently used. In this study, we propose an application of biomedical imaging based on performing the reconstruction of a phantom image via an in-line digital holography technique. Hence, many different sub-tissues can be imaged at the same time without the storage problem of the reconstructed image. To neglect the biopsy process required in medical imaging, the phantom image is obtained by using a linear array transducer for this study. We present the performance evaluation of the simulation results for the proposed technique by calculating the error metrics such as mean squared error (MSE), mean absolute error (MAE), and peak signal-to-noise ratio (PSNR). The obtained results reveal that the reconstructed images are well-matched to the original images, which are desired to be displayed by the holography technique.
Highlights
IMAGING TECHNOLOGY is conventionally used both for the detection and localization of disease and mapping the anatomy of the human body
We propose an application of biomedical imaging based on performing the reconstruction of a phantom image via an in-line digital holography technique
Biomedical optical imaging (BOI) methods are based on transferring a light beam through the tissue and collecting photons that escape from the tissue surface
Summary
IMAGING TECHNOLOGY is conventionally used both for the detection and localization of disease and mapping the anatomy of the human body. From other medical imaging techniques such as x-rays, since visible light and photons are used in optical imaging, it is possible to achieve more detailed image versions of the body region of interest [4]. It enables smaller structures such as cells and molecules to be visualized. Perhaps most importantly, is that the optical imaging decimates the harmful radiation to which the patient is exposed Another one is that, unlike other imaging techniques, in optical imaging, many different features of an organ or a tissue can be seen and measured at the same time by using various light colors. To obtain the three dimensional (3D) medical images, the reconstruction process is required where the series of images are sliced from a target sub-tissue [17,18,19]
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