Reconstruction of undersampled radial free-breathing 3D abdominal MRI using stacked convolutional auto-encoders.

Abstract

Free-breathing three-dimensional (3D) abdominal imaging is a challenging task for MRI, as respiratory motion severely degrades image quality. One of the most promising self-navigation techniques is the 3D golden-angle radial stack-of-stars (SOS) sequence, which has advantages in terms of speed, resolution, and allowing free breathing. However, streaking artifacts are still clearly observed in reconstructed images when undersampling is applied. This work presents a novel reconstruction approach based on a stacked convolutional auto-encoder (SCAE) network to solve this problem. Thirty healthy volunteers participated in our experiment. To build the dataset, reference and artifact-affected images were reconstructed using 451 golden-angle spokes and the first 20, 40, or 90 golden-angle spokes corresponding to acceleration rates of 31.4, 15.7, and 6.98, respectively. In the training step, we trained the SCAE by feeding it with patches from artifact-affected images. The SCAE outputs patches in the corresponding reference images. In the testing step, we applied the trained SCAE to map each input artifact-affected patch to the corresponding reference image patch. The SCAE-based reconstruction images with acceleration rates of 6.98 and 15.7 show nearly similar quality as the reference images. Additionally, the calculation time is below 1 s. Moreover, the proposed approach preserves important features, such as lesions not presented in the training set. The preliminary results demonstrate the feasibility of the proposed SCAE-based strategy for correcting the streaking artifacts of undersampled free-breathing 3D abdominal MRI with a negligible reconstruction time.