Abstract

Improving the resolution of medical images is crucial in diagnosis, feature extraction, and data retrieval. A significant group of super-resolution algorithms is multi-frame techniques. However, they are not appropriate to medical data since they need several frames of the same scene, which bring a high risk of radiation or require a considerable acquisition time. We propose a new data augmentation technique and employ it in a multi-frame image reconstruction algorithm to improve the resolution of pathologic liver CT images. The input to our algorithm is a 3D CT-scan of the abdominal region. Neighboring slices are considered to increase the resolution of a single slice. Augmented slices are prepared using the nearby slices and the interpolation approach. The new data is aligned to the original slice, and it is used as an augmented version of the data. Then, a multi-frame scheme is utilized to reconstruct the high-resolution image. Our method’s novelty is to remove the need for multiple scans of a patent to employ multi-resolution techniques in medical applications. The results reveal that the proposed method is superior to conventional interpolation methods and available augmentation techniques. Compared to the tricubic interpolation, the proposed method improved the PSNR by 3.1. Concerning conventional augmentation techniques, it enhanced the SSIM measure by 0.06. The proposed algorithm improved the SSIM by 0.11 compared to traditional interpolation techniques and 0.1 for recent researches. Therefore, a multi-frame super-resolution technique has the potential to reconstruct medical data better.

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