Abstract

INTRODUCTION The carotid bifurcation (CB) is a commonly known site for clinically significant atherosclerosis. Over the past decades, many research works demonstrated that the shear stress of blood on the vessel wall (wall shear stress; WSS) is implicated in plaque development. Nonetheless, these findings still remain as a hypothesis which is yet to be ascertained. This is partially due to the lack of patient specific anatomically realistic CB model obtained before and after plaque formation. Without the hemodynamics data before the plaque formation, it is not feasible to confirm the role of WSS in plaque formation. With the aim of providing another angle of investigation, this paper presents some preliminary results of an on-going project attempting to verify the hypothesis by reconstructing the blood flow pattern within the artery before and after plaque development in a patient specific manner.

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