Reconstruction of Biliary Tract:Interposition of Gallbladder Between Common Hepatic Duct and Duodenum in Animal Models

Abstract

Objective:To investigate the feasibility to interpose the gallbladder between common hepatic duct and duodenum for bile duct reconstruction in animal models.Methods:This experiment was carried out on 15 dogs.Of them,the gallbladder interposition between the common hepatic duct and duodenum was performed on 10 and the gallbladder biopsy on 5.A resting pressure of gallbladder and an antireflux pressure from duodenum to the interposed gallbladder were measured.The concentration and storage function of the interposed gallbladder were evaluated by oral cistobil cholecystography.Results:All animals were alive at termination of the study 12 weeks postoperatively.There was no difference in body weight between the two groups.When the experimental group was reoperated on,the bile in the interposed gallbladder was clear and without food residue.The resting pressure in gallbladder increased from 0.91±0.47 kPa prcoperation to 1.55±0.56 kPa postoperation.The anti-reflux pressure from duodenum to the interposed gallbladder was 18.99±5.69 kPa.Postoperative X-ray exams revealed that the interposed gallbladder pressrved the bile storage,concentration and excretion functions.Conclusions;The interposition of gallbladder can be used to reconstruct the bile duct and preserve the functions of the gallbladder. Key words: Gallbladder; Reconstruction of bile duct; Common bile duct; Duodenum