Abstract
The actin and microtubule cytoskeletons form active networks in the cell that play vital roles in cellular processes such as cell division and motility. Crosstalk between these two cytoskeletal systems is mediated by cross-linking proteins with affinity for both types of filaments. I will provide an overview of in vitro experiments in which we study how different types of actin-microtubule crosslinking proteins may lead to filament bundling, guidance of microtubule growth and even active transport of actin filaments by growing microtubule ends.
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