Abstract
We show that a recombinational repair mechanism for DNA lesions can be expected to produce exactly the types of exceptions to the usually observed semiconservative segregation of newly synthetized DNA that have been reported in the literature. This removes the obstacles their occurrence appearance to present to the interpretation that the eukaryote chromosome is mononeme, containing but a single DNA double helix prior to replication. We further note that such a recombinational repair system would generate single sister chromatid exchange (SCE) events but not twin SCE events. This, along with other factors, complicates the interpretation of single: twin ratios in terms of any particular model of eukaryote chromosome structure.
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