Abstract

Recombinant activated factor VII, (rFVIIa, NovoSeven®, Novo Nordisk), is licensed in the UK, Europe and US for treatment of haemophilia patients with inhibitors to factors VII and IX, during bleeding episodes occurring spontaneously or caused by trauma or surgery. It has been approved for use in patients with factor VII deficiency and Glanzmann’s thrombasthenia. [1] O’Connell Wood J.J. Wise R.P. et al. Thromboembolic adverse effects after use of recombinant human coagulation factor VIIa. JAMA. 2006; 295: 293-298 Crossref PubMed Scopus (575) Google Scholar It is not licensed for use in any other group of patients.

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